Calculator
Osmolar Clearance Calculator
Calculate osmolar clearance from urine and serum osmolality and urine flow.
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All fields required unless notedEnter your values and press Calculate to see the result.
Formula & Clinical Notes
Formula
COsm = (UOsm × V) / SOsm
Clinical Notes
Osmolar clearance (COsm) is the volume of plasma cleared of osmotically active solutes per minute. It combines with free water clearance to describe renal water handling: urine flow = osmolar clearance + free water clearance.
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