Systemic Immune-Inflammation Index Calculator

Calculate the systemic immune-inflammation index from the complete blood count.

Aug 31, 2026 Hematology #inflammation #sii

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All fields required unless noted

Platelet count (10^9/L)

Absolute neutrophil count (10^9/L)

Absolute lymphocyte count (10^9/L)

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Enter your values and press Calculate to see the result.

Formula & Clinical Notes

Formula

SII = (Platelet Count × Absolute Neutrophil Count) / Absolute Lymphocyte Count

Clinical Notes

The systemic immune-inflammation index (SII = platelet × neutrophil / lymphocyte) integrates three blood count lines as a prognostic inflammation marker, particularly studied in oncology. Elevated values have been associated with worse outcomes.

Sources

Systemic immune-inflammation index as a prognostic marker