Bilirubin Ratio Calculator

Calculate the direct to total bilirubin ratio and indirect bilirubin.

Aug 31, 2026 Clinical Chemistry #bilirubin #jaundice #conjugated #unconjugated

Calculate

All fields required unless noted

Total bilirubin (mg/dL)

Direct (conjugated) bilirubin (mg/dL)

Calculating...

Enter your values and press Calculate to see the result.

Reference Ranges Used

Indirect (Unconjugated) Bilirubin - Adult 0.1–1 mg/dL

Formula & Clinical Notes

Formula

Indirect = Total − Direct; Direct/Total × 100%

Clinical Notes

Indirect bilirubin = total − direct. The direct/total ratio classifies hyperbilirubinaemia: a ratio < 15–20% indicates predominantly unconjugated hyperbilirubinaemia (haemolysis, Gilbert syndrome), while a ratio > 20% (and typically > 50%) indicates conjugated (cholestatic or hepatocellular) hyperbilirubinaemia.

Sources

StatPearls — Unconjugated Hyperbilirubinemia
StatPearls — Hyperbilirubinemia