Corrected Total Protein Calculator

Correct plasma total protein for the fibrinogen contribution.

Aug 31, 2026 Clinical Chemistry #total-protein #fibrinogen #plasma #serum

Calculate

All fields required unless noted

Plasma total protein (g/dL)

Fibrinogen (g/dL)

Calculating...

Enter your values and press Calculate to see the result.

Formula & Clinical Notes

Formula

Corrected TP = Plasma Total Protein − Fibrinogen

Clinical Notes

Total protein measured on plasma includes fibrinogen, which is absent from serum. Subtract the measured plasma fibrinogen to obtain the corrected total protein (serum-equivalent value). This is relevant when comparing plasma and serum measurements. Typical plasma fibrinogen is approximately 0.2–0.4 g/dL.

Sources

Bakker et al. (1992) — Clin Chem 38:2221 — Plasma protein references