Calculator
Bicarbonate Gap Calculator
Calculate the bicarbonate gap to detect mixed acid-base disorders.
Fluids, Electrolytes & Acid Base
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Formula & Clinical Notes
Formula
Bicarbonate Gap = AG − (24 − HCO₃)
Clinical Notes
The bicarbonate gap = anion gap − (24 − measured HCO₃), where 24 mEq/L is the normal bicarbonate reference. In a single (pure) anion gap metabolic acidosis the bicarbonate gap remains near the normal anion gap (~12 mEq/L). A bicarbonate gap above ~12 suggests a superimposed metabolic alkalosis (or a baseline elevated bicarbonate); a gap below ~12 suggests a superimposed non-anion gap (hyperchloremic) metabolic acidosis. This complements the separate Delta Gap and Delta Ratio calculators.
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