Albumin/Globulin Ratio Calculator

Calculate the albumin to globulin (A/G) ratio.

Aug 31, 2026 Clinical Chemistry #albumin-globulin #ag-ratio #proteins #myeloma

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All fields required unless noted

Serum albumin (g/dL)

Total protein (g/dL)

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Reference Ranges Used

A/G (Albumin/Globulin) Ratio - Adult 1.1–2.5 ratio

Formula & Clinical Notes

Formula

A/G Ratio = Albumin ÷ (Total Protein − Albumin)

Clinical Notes

The A/G ratio is albumin divided by globulin (total protein minus albumin). Normal values are usually between 1.1 and 2.5. A low ratio reflects either low albumin (cirrhosis, nephrotic syndrome, malnutrition) or high globulins (multiple myeloma, chronic inflammation, autoimmune disease). A reversed A/G ratio (< 1.0) is classically seen in multiple myeloma and chronic infection.

Sources

NCBI Bookshelf — Serum Albumin and Globulin (Clinical Methods)