NAFLD Fibrosis Score Calculator

Calculate the NAFLD fibrosis score to stage liver fibrosis in NAFLD.

Aug 31, 2026 Clinical Chemistry #fibrosis #nafld-fibrosis-score #nfs #nafld

Calculate

All fields required unless noted

Age (years)

BMI (kg/m²)

Impaired fasting glucose or diabetes

AST (U/L)

ALT (U/L)

Platelet count (10⁹/L)

Serum albumin (g/dL)

Calculating...

Enter your values and press Calculate to see the result.

Formula & Clinical Notes

Formula

NFS = −1.675 + 0.037×Age + 0.094×BMI + 1.13×IFG + 0.99×AST/ALT − 0.013×Platelet − 0.66×Albumin

Clinical Notes

The NAFLD fibrosis score uses age, BMI, impaired fasting glucose/diabetes, AST/ALT, platelet count and albumin. A score < −1.455 excludes advanced fibrosis; a score > 0.676 predicts advanced fibrosis; values in between are indeterminate. It was derived and validated in biopsy-proven NAFLD.

Sources

Angulo et al. (2007) — The NAFLD fibrosis score