Standard Operating Procedures
Laboratory SOPs
Standard operating procedures for laboratory professionals, from specimen collection to instrument quality control.
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Clotting Time
A basic manual screening procedure for observing the time required for whole blood to clot under standardized conditions.
Bleeding Time
A historical primary haemostasis screening procedure that measures the time required for bleeding to stop after a standardized skin injury.
PT/APTT Mixing (Correction) Study
SOP for the 1:1 plasma mixing study to distinguish factor deficiency from circulating inhibitor in prolonged PT or APTT.
Thrombin Time Testing
SOP for the thrombin time to detect hypofibrinogenemia, dysfibrinogenemia, DIC, and heparin contamination.
Fibrinogen Testing (Clauss Method)
SOP for functional fibrinogen by the Clauss method for DIC, dysfibrinogenemia, and hemorrhagic risk assessment.
D-Dimer Testing Procedure
Standard Operating Procedure (SOP) for quantitative and semi-quantitative D-dimer testing using immunoassay methods for the evaluation of thrombotic disorders.
Activated Partial Thromboplastin Time (APTT)
SOP for evaluating the intrinsic and common coagulation pathways and monitoring unfractionated heparin therapy.
Prothrombin Time (PT) and INR
SOP for evaluating the extrinsic and common coagulation pathways and monitoring oral anticoagulant therapy.